Neurohormonal activation induces intracellular iron deficiency and mitochondrial dysfunction in cardiac cells

Neurohormonal activation induces intracellular iron deficiency and mitochondrial dysfunction in cardiac cells

Abstract Background Iron deficiency (ID) is common in patients with heart failure (HF) and is associated with poor outcomes, yet its role in the pathophysiology of HF is not well-defined. We sought to determine the consequences of HF neurohormonal activation in iron homeostasis and mitochondrial fun...

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Bibliographic Details
Main Authors: M. Tajes, C. Díez-López, C. Enjuanes, P. Moliner, J. L. Ferreiro, A. Garay, S. Jiménez-Marrero, S. Yun, S. G. Sosa, L. Alcoberro, J. González-Costello, E. García-Romero, L. Yañez-Bisbe, B. Benito, J. Comín-Colet
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Cell & Bioscience
Subjects:
Neurohormonal activation
Heart failure
Iron deficiency
Cardiac cell
Mitochondria function
Online Access:https://doi.org/10.1186/s13578-021-00605-5

Internet

https://doi.org/10.1186/s13578-021-00605-5

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