Association of single nucleotide polymorphisms in the lens epithelium-derived growth factor (LEDGF/p75) with HIV-1 infection outcomes in Brazilian HIV-1+ individuals.

Association of single nucleotide polymorphisms in the lens epithelium-derived growth factor (LEDGF/p75) with HIV-1 infection outcomes in Brazilian HIV-1+ individuals.

The lens epithelium-derived growth factor p75 (LEDGF/p75), coded by the PSIP1 gene, is an important host co-factor that interacts with HIV-1 integrase to target integration of viral cDNA into active genes. The aim of this study was to investigate the association of SNPs in the PSIP1 gene with diseas...

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Bibliographic Details
Main Authors: Caroline Pereira Bittencourt Passaes, Cynthia Chester Cardoso, Diogo Gama Caetano, Sylvia Lopes Maia Teixeira, Monick Lindenmeyer Guimarães, Dayse Pereira Campos, Valdilea Gonçalves Veloso, Dunja Z Babic, Mario Stevenson, Milton Ozório Moraes, Mariza Gonçalves Morgado
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4105638?pdf=render

Internet

http://europepmc.org/articles/PMC4105638?pdf=render

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