Peptide binding properties of the three PDZ domains of Bazooka (Drosophila Par-3).

The Par complex is a conserved cell polarity regulator. Bazooka/Par-3 is scaffold for the complex and contains three PDZ domains in tandem. PDZ domains can act singly or synergistically to bind the C-termini of interacting proteins. Sequence comparisons among Drosophila Baz and its human and C. eleg...

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Bibliographic Details
Main Authors: Cao Guo Yu, Raffi Tonikian, Corinna Felsensteiner, Jacquelyn R Jhingree, Darrell Desveaux, Sachdev S Sidhu, Tony J C Harris
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3899232?pdf=render