Induction of NTPDase1/CD39 by Reactive Microglia and Macrophages Is Associated With the Functional State During EAE

Purinergic signaling is critically involved in neuroinflammation associated with multiple sclerosis (MS) and its major inflammatory animal model, experimental autoimmune encephalomyelitis (EAE). Herein, we explored the expression of ectonucleoside triphosphate diphosphohydrolase1 (NTPDase1/CD39) in...

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Bibliographic Details
Main Authors: Marija Jakovljevic, Irena Lavrnja, Iva Bozic, Ana Milosevic, Ivana Bjelobaba, Danijela Savic, Jean Sévigny, Sanja Pekovic, Nadezda Nedeljkovic, Danijela Laketa
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Neuroscience
Subjects:
EAE
ATP
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.00410/full