Oxidation of p62 as an evolutionary adaptation to promote autophagy in stress conditions
Ageing and age-related diseases are characterised by increased oxidative and proteotoxic stress, which results in negative effects on cell function and survival. The cell possesses several mechanisms to deal with damaged proteins, including degradation via macroautophagy (hereafter called autophagy)...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Shared Science Publishers OG
2018-03-01
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| Series: | Cell Stress |
| Subjects: | |
| Online Access: | http://www.cell-stress.com/researcharticles/oxidation-of-p62-as-an-evolutionary-adaptation-to-promote-autophagy-in-stress-conditions/ |