A vanillin derivative causes mitochondrial dysfunction and triggers oxidative stress in Cryptococcus neoformans.

Vanillin is a well-known food and cosmetic additive and has antioxidant and antimutagenic properties. It has also been suggested to have antifungal activity against major human pathogenic fungi, although it is not very effective. In this study, the antifungal activities of vanillin and 33 vanillin d...

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Bibliographic Details
Main Authors: Jin Hyo Kim, Han-Ok Lee, Yong-Joon Cho, Jeongmi Kim, Jongsik Chun, Jaehyuk Choi, Younghoon Lee, Won Hee Jung
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3930674?pdf=render