Anti-Tumor Effects of Sodium Meta-Arsenite in Glioblastoma Cells with Higher Akt Activities

Anti-Tumor Effects of Sodium Meta-Arsenite in Glioblastoma Cells with Higher Akt Activities

Glioblastoma is a type of aggressive brain tumor that grows very fast and evades surrounding normal brain, lead to treatment failure. Glioblastomas are associated with Akt activation due to somatic alterations in PI3 kinase/Akt pathway and/or PTEN tumor suppressor. Sodium meta-arsenite, KML001 is an...

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Bibliographic Details
Main Authors: Eun Jeong Lee, Jee Young Sung, Kyung Hee Koo, Jong Bae Park, Dae Hong Kim, Jaegal Shim, Chang Hoon Lee, Jongsun Park, Yong-Nyun Kim
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:International Journal of Molecular Sciences
Subjects:
glioblastoma
PTEN
Akt
sodium meta-arsenite
Online Access:https://www.mdpi.com/1422-0067/21/23/8982

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https://www.mdpi.com/1422-0067/21/23/8982

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