Hunchback is counter-repressed to regulate even-skipped stripe 2 expression in Drosophila embryos.

Hunchback is a bifunctional transcription factor that can activate and repress gene expression in Drosophila development. We investigated the regulatory DNA sequence features that control Hunchback function by perturbing enhancers for one of its target genes, even-skipped (eve). While Hunchback dire...

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Bibliographic Details
Main Authors: Ben J Vincent, Max V Staller, Francheska Lopez-Rivera, Meghan D J Bragdon, Edward C G Pym, Kelly M Biette, Zeba Wunderlich, Timothy T Harden, Javier Estrada, Angela H DePace
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-09-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC6145585?pdf=render