Herpes simplex virus-1 infects the olfactory bulb shortly following ocular infection and exhibits a long-term inflammatory profile in the form of effector and HSV-1-specific T cells

Herpes simplex virus-1 infects the olfactory bulb shortly following ocular infection and exhibits a long-term inflammatory profile in the form of effector and HSV-1-specific T cells

Abstract Background Herpes simplex virus 1 (HSV-1) infection can result in a life-threatening condition known as herpes simplex encephalitis (HSE). Trafficking patterns by which the virus reaches the central nervous system (CNS) following ocular infection are unresolved. We evaluated early viral dis...

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Bibliographic Details
Main Authors: Chandra M. Menendez, Daniel J. J. Carr
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Journal of Neuroinflammation
Subjects:
HSV-1
Dissemination
Olfactory bulb
Long-term inflammation
Online Access:http://link.springer.com/article/10.1186/s12974-017-0903-9

Internet

http://link.springer.com/article/10.1186/s12974-017-0903-9

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