HIV induces airway basal progenitor cells to adopt an inflammatory phenotype

Abstract Despite the introduction of anti-retroviral therapy, chronic HIV infection is associated with an increased incidence of other comorbidities such as COPD. Based on the knowledge that binding of HIV to human airway basal stem/progenitor cells (BC) induces a destructive phenotype by increased...

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Bibliographic Details
Main Authors: Nancy P. Y. Chung, K. M. Faisal Khan, Robert J. Kaner, Sarah L. O’Beirne, Ronald G. Crystal
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-82143-1