A novel approach to measuring macrophage-specific reverse cholesterol transport in vivo in humans

A novel approach to measuring macrophage-specific reverse cholesterol transport in vivo in humans

Reverse cholesterol transport (RCT) is thought to be an atheroprotective function of HDL, and macrophage-specific RCT in mice is inversely associated with atherosclerosis. We developed a novel method using 3H-cholesterol nanoparticles to selectively trace macrophage-specific RCT in vivo in humans. U...

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Bibliographic Details
Main Authors: Marina Cuchel, Anna C. Raper, Donna M. Conlon, Daniel A. Pryma, Richard H. Freifelder, Rahul Poria, Debra Cromley, Xiaoyu Li, Richard L. Dunbar, Benjamin French, Liming Qu, William Farver, Ching-Chiang Su, Sissel Lund-Katz, Amanda Baer, Giacomo Ruotolo, Peter Akerblad, Carol S. Ryan, Lan Xiao, Todd G. Kirchgessner, John S. Millar, Jeffrey T. Billheimer, Daniel J. Rader
Format: Article
Language:English
Published: Elsevier 2017-04-01
Series:Journal of Lipid Research
Subjects:
lipoproteins
high density lipoprotein
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520338529

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http://www.sciencedirect.com/science/article/pii/S0022227520338529

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