TROAP switches DYRK1 activity to drive hepatocellular carcinoma progression
Abstract Hepatocellular carcinoma (HCC) is one of the common malignancy and lacks effective therapeutic targets. Here, we demonstrated that ectopic expression of trophinin-associated protein (TROAP) dramatically drove HCC cell growth assessed by foci formation in monolayer culture, colony formation...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-01-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-021-03422-3 |