Wharton’s Jelly Mesenchymal Stromal Cells Support the Expansion of Cord Blood–derived CD34 Cells Mimicking a Hematopoietic Niche in a Direct Cell–cell Contact Culture System

Wharton’s Jelly Mesenchymal Stromal Cells Support the Expansion of Cord Blood–derived CD34 Cells Mimicking a Hematopoietic Niche in a Direct Cell–cell Contact Culture System

Wharton’s jelly mesenchymal stromal cells (WJ-MSCs) have been recently exploited as a feeder layer in coculture systems to expand umbilical cord blood–hematopoietic stem/progenitor cells (UCB-HSPCs). Here, we investigated the role of WJ-MSCs in supporting ex vivo UCB-HSPC expansion either when cultu...

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Bibliographic Details
Main Authors: Melania Lo Iacono, Eleonora Russo, Rita Anzalone, Elena Baiamonte, Giusi Alberti, Aldo Gerbino, Aurelio Maggio, Giampiero La Rocca, Santina Acuto
Format: Article
Language:English
Published: SAGE Publishing 2018-01-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/0963689717737089

Internet

https://doi.org/10.1177/0963689717737089

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