Salvinorin A preserves cerebral pial artery autoregulation after forebrain ischemia via the PI3K/AKT/cGMP pathway

Salvinorin A preserves cerebral pial artery autoregulation after forebrain ischemia via the PI3K/AKT/cGMP pathway

This study aimed to investigate the protective effect of salvinorin A on the cerebral pial artery after forebrain ischemia and explore related mechanisms. Thirty Sprague-Dawley rats received forebrain ischemia for 10 min. The dilation responses of the cerebral pial artery to hypercapnia and hypotens...

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Bibliographic Details
Main Authors: H.P. Dong, W. Zhou, X.X. Ma, Z.Z. He, Z.H. Wang
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2018-03-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Salvinorin A
Cerebral pial artery
Dilation
Forebrain ischemia
PI3K/AKT/cGMP pathway
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000500604&lng=en&tlng=en

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000500604&lng=en&tlng=en

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