Reactive Oxygen Species Formation in the Brain at Different Oxygen Levels: The Role of Hypoxia Inducible Factors

Hypoxia inducible factor (HIF) is the master oxygen sensor within cells and is central to the regulation of cell responses to varying oxygen levels. HIF activation during hypoxia ensures optimum ATP production and cell integrity, and is associated both directly and indirectly with reactive oxygen sp...

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Bibliographic Details
Main Authors: Ruoli Chen, U Hin Lai, Lingling Zhu, Ayesha Singh, Muhammad Ahmed, Nicholas R. Forsyth
Format: Article
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Cell and Developmental Biology
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