A tutorial review of mathematical techniques for quantifying tumor heterogeneity
Intra-tumor and inter-patient heterogeneity are two challenges in developing mathematical models for precision medicine diagnostics. Here we review several techniques that can be used to aid the mathematical modeller in inferring and quantifying both sources of heterogeneity from patient data. These...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
AIMS Press
2020-05-01
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Series: | Mathematical Biosciences and Engineering |
Subjects: | |
Online Access: | https://www.aimspress.com/article/doi/10.3934/mbe.2020207?viewType=HTML |