Expression of Lectin-Like Transcript 1, the Ligand for CD161, in Rheumatoid Arthritis.

Expression of Lectin-Like Transcript 1, the Ligand for CD161, in Rheumatoid Arthritis.

Precursor Th17 lineage cells expressing CD161 are implicated in Rheumatoid Arthritis (RA) pathogenesis. CD4+CD161+ T-cells accumulate in RA joints and may acquire a non classical Th1 phenotype. The endogenous ligand for CD161 is lectin-like transcript 1 (LLT1). CD161/LLT1 ligation may co-stimulate T...

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Bibliographic Details
Main Authors: Paulina Chalan, Johan Bijzet, Minke G Huitema, Bart-Jan Kroesen, Elisabeth Brouwer, Annemieke M H Boots
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4492745?pdf=render

Internet

http://europepmc.org/articles/PMC4492745?pdf=render

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