Defining potency of CAR+ T cells: Fast and furious or slow and steady

Defining potency of CAR+ T cells: Fast and furious or slow and steady

Genetically engineered T cells that express chimeric antigen receptors (CAR+) are heterogeneous and thus, understanding the immunotherapeutic efficacy remains a challenge in adoptive cell therapy. We developed a high-throughput single-cell methodology, Timelapse Imaging Microscopy In Nanowell Grids...

Full description

Bibliographic Details
Main Authors: Ivan Liadi, Harjeet Singh, Gabrielle Romain, Badrinath Roysam, Laurence JN Cooper, Navin Varadarajan
Format: Article
Language:English
Published: Taylor & Francis Group 2019-10-01
Series:OncoImmunology
Subjects:
single cell
nanowell
timelapse microscopy
timing
activation induced cell death
cytolysis
immunotherapy
Online Access:http://dx.doi.org/10.1080/2162402X.2015.1051298

Internet

http://dx.doi.org/10.1080/2162402X.2015.1051298

Similar Items