The Rabies Virus L Protein Catalyzes mRNA Capping with GDP Polyribonucleotidyltransferase Activity

The large (L) protein of rabies virus (RABV) plays multiple enzymatic roles in viral RNA synthesis and processing. However, none of its putative enzymatic activities have been directly demonstrated in vitro. In this study, we expressed and purified a recombinant form of the RABV L protein and verifi...

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Bibliographic Details
Main Authors: Minako Ogino, Naoto Ito, Makoto Sugiyama, Tomoaki Ogino
Format: Article
Language:English
Published: MDPI AG 2016-05-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/8/5/144