Overexpression of Grb2-associated Binder 2 in Human Lung Cancer

<p><b>Objective</b>: Grb2-associated binder 2 (Gab2), a member of the family of Gab scaffolding adaptors, transmits and amplifies the signals from receptor tyrosine kinases. A recent study demonstrated that Gab2 was over-expressed in breast cancers and metastatic melanomas, and Gab...

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Bibliographic Details
Main Author: Xiu-Li Xu, Xia Wang, Zhao-Li Chen, Min Jin, Wu Yang, Guo-Fan Zhao, Jun-Wen Li
Format: Article
Language:English
Published: Ivyspring International Publisher 2011-01-01
Series:International Journal of Biological Sciences
Online Access:http://www.biolsci.org/v07p0496.htm