Molecular landscape and targeted therapy of acute myeloid leukemia

Abstract For decades, genetic aberrations including chromosome and molecular abnormalities are important diagnostic and prognostic factors in acute myeloid leukemia (AML). ATRA and imatinib have been successfully used in AML and chronic myelogenous leukemia, which proved that targeted therapy by ide...

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Bibliographic Details
Main Authors: Runxia Gu, Xue Yang, Hui Wei
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Biomarker Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40364-018-0146-7