Ozone-Induced Aryl Hydrocarbon Receptor Activation Controls Lung Inflammation via Interleukin-22 Modulation

Ozone-Induced Aryl Hydrocarbon Receptor Activation Controls Lung Inflammation via Interleukin-22 Modulation

Airborne ozone exposure causes severe lung injury and inflammation. The aryl hydrocarbon Receptor (AhR) (1), activated in pollutant-induced inflammation, is critical for cytokine production, especially IL-22 and IL-17A. The role of AhR in ozone-induced lung inflammation is unknown. We report here th...

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Bibliographic Details
Main Authors: Chloé Michaudel, Florent Bataille, Isabelle Maillet, Louis Fauconnier, Cyril Colas, Harry Sokol, Marjolène Straube, Aurélie Couturier-Maillard, Laure Dumoutier, Jacques van Snick, Valérie F. Quesniaux, Dieudonnée Togbe, Bernhard Ryffel
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Immunology
Subjects:
ozone
AhR
ILC3
T cells
inflammation
IL-17
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00144/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00144/full

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