Molecular Targeting Therapy against EGFR Family in Breast Cancer: Progress and Future Potentials

Molecular Targeting Therapy against EGFR Family in Breast Cancer: Progress and Future Potentials

：The<b> </b>epidermal growth factor receptor (EGFR) family contains four transmembrane tyrosine kinases (EGFR1/ErbB1, Her2/ErbB2, Her3/ErbB3 and Her4/ErbB4) and 13 secreted polypeptide ligands. EGFRs are overexpressed in many solid tumors, including breast, pancreas, head-and-neck, prost...

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Bibliographic Details
Main Authors: Amaia Eleonora Maennling, Mehmet Kemal Tur, Marcus Niebert, Torsten Klockenbring, Felix Zeppernick, Stefan Gattenlöhner, Ivo Meinhold-Heerlein, Ahmad Fawzi Hussain
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Cancers
Subjects:
epidermal growth factor receptor
antibody
antibody drug conjugate
tyrosine kinase inhibitor
chimeric antigen receptors t cells
Online Access:https://www.mdpi.com/2072-6694/11/12/1826

Internet

https://www.mdpi.com/2072-6694/11/12/1826

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