Wnt-PLC-IP3-Connexin-Ca2+ axis maintains ependymal motile cilia in zebrafish spinal cord

Wnt-PLC-IP3-Connexin-Ca2+ axis maintains ependymal motile cilia in zebrafish spinal cord

Ependymal cells are supporting cells in the central nervous system. Here the authors elucidate a signalling axis in zebrafish spinal cord ependymal cells that is important for motile cilia assembly and maintenance, demonstrating that it depends on intercellular propagation of calcium ions via connex...

Full description

Bibliographic Details
Main Authors: Jun Zhang, Gopalakrishnan Chandrasekaran, Wenting Li, Dong-Young Kim, In Young Jeong, So-Hyun Lee, Ting Liang, Jin Young Bae, Isaac Choi, Hyuno Kang, Jin-Soo Maeng, Myeong-Kyu Kim, Taewon Lee, Seung Woo Park, Min Jung Kim, Hyung-Seok Kim, Hyunju Ro, Yong Chul Bae, Hae-Chul Park, Eun Young Choi, Seok-Yong Choi
Format: Article
Language:English
Published: Nature Publishing Group 2020-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-15248-2

Internet

https://doi.org/10.1038/s41467-020-15248-2

Similar Items