CD4⁺ T cells expressing latency-associated peptide and Foxp3 are an activated subgroup of regulatory T cells enriched in patients with colorectal cancer.

CD4⁺ T cells expressing latency-associated peptide and Foxp3 are an activated subgroup of regulatory T cells enriched in patients with colorectal cancer.

Latency-associated peptide (LAP) - expressing regulatory T cells (Tregs) are important for immunological self-tolerance and immune homeostasis. In order to investigate the role of LAP in human CD4⁺Foxp3⁺ Tregs, we designed a cross-sectional study that involved 42 colorectal cancer (CRC) patients. Th...

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Bibliographic Details
Main Authors: Jayashri Mahalingam, Chun-Yen Lin, Jy-Ming Chiang, Po-Jung Su, Yu-Yi Chu, Hsin-Yi Lai, Jian-He Fang, Ching-Tai Huang, Yung-Chang Lin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4182495?pdf=render

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http://europepmc.org/articles/PMC4182495?pdf=render

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