Success of prophylactic antiviral therapy for SARS-CoV-2: Predicted critical efficacies and impact of different drug-specific mechanisms of action.

Success of prophylactic antiviral therapy for SARS-CoV-2: Predicted critical efficacies and impact of different drug-specific mechanisms of action.

Repurposed drugs that are safe and immediately available constitute a first line of defense against new viral infections. Despite limited antiviral activity against SARS-CoV-2, several drugs are being tested as medication or as prophylaxis to prevent infection. Using a stochastic model of early phas...

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Bibliographic Details
Main Authors: Peter Czuppon, Florence Débarre, Antonio Gonçalves, Olivier Tenaillon, Alan S Perelson, Jérémie Guedj, François Blanquart
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-03-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1008752

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https://doi.org/10.1371/journal.pcbi.1008752

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