Transcriptomes of antigen presenting cells in human thymus.

Antigen presenting cells (APCs) in the thymus play an essential role in the establishment of central tolerance, i.e. the generation of a repertoire of functional and self-tolerant T cells to prevent autoimmunity. In this study, we have compared the transcriptomes of four primary APCs from human thym...

Full description

Bibliographic Details
Main Authors: Ingvild S M Gabrielsen, Hanna Helgeland, Helle Akselsen, Hans Christian D Aass, Arvind Y M Sundaram, Isaac V Snowhite, Alberto Pugliese, Siri T Flåm, Benedicte A Lie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0218858