Cell culture models demonstrate that CFTR dysfunction leads to defective fatty acid composition and metabolism*

Cell culture models demonstrate that CFTR dysfunction leads to defective fatty acid composition and metabolism*

Cystic fibrosis (CF) is associated with fatty acid alterations characterized by low linoleic and docosahexaenoic acid. It is not clear whether these fatty acid alterations are directly linked to cystic fibrosis transmembrane conductance regulator (CFTR) dysfunction or result from nutrient malabsorpt...

Full description

Bibliographic Details
Main Authors: Charlotte Andersson, M. Rabie Al-Turkmani, Juanito E. Savaille, Ragheed Alturkmani, Waddah Katrangi, Joanne E. Cluette-Brown, Munir M. Zaman, Michael Laposata, Steven D. Freedman
Format: Article
Language:English
Published: Elsevier 2008-08-01
Series:Journal of Lipid Research
Subjects:
cystic fibrosis transmembrane conductance regulator
essential fatty acid deficiency
fetal bovine serum
horse serum
arachidonic acid
docosahexaenoic acid
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520346873

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520346873

Similar Items