Macrophage activation in acute exacerbation of idiopathic pulmonary fibrosis.

BACKGROUND:Acute exacerbation (AE) of idiopathic pulmonary fibrosis (IPF) is a common cause of disease acceleration in IPF and has a major impact on mortality. The role of macrophage activation in AE of IPF has never been addressed before. METHODS:We evaluated BAL cell cytokine profiles and BAL diff...

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Bibliographic Details
Main Authors: Jonas Christian Schupp, Harald Binder, Benedikt Jäger, Giuseppe Cillis, Gernot Zissel, Joachim Müller-Quernheim, Antje Prasse
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4295887?pdf=render