An evolutionary switch in ND2 enables Src kinase regulation of NMDA receptors

An evolutionary switch in ND2 enables Src kinase regulation of NMDA receptors

N-methyl D-aspartate receptor (NMDAR) activity is modulated by Src tyrosine kinase via the mitochondrial protein NADH dehydrogenase subunit 2 (ND2). Here the authors show that ND2 interacts with the transmembrane region of NMDAR GluN1 subunit, a process that is crucial for Src regulation of NMDAR ac...

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Bibliographic Details
Main Authors: David P. Scanlon, Alaji Bah, Mickaël Krzeminski, Wenbo Zhang, Heather L. Leduc-Pessah, Yi Na Dong, Julie D. Forman-Kay, Michael W. Salter
Format: Article
Language:English
Published: Nature Publishing Group 2017-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms15220

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https://doi.org/10.1038/ncomms15220

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