7-Acetylsinumaximol B Induces Apoptosis and Autophagy in Human Gastric Carcinoma Cells through Mitochondria Dysfunction and Activation of the PERK/eIF2α/ATF4/CHOP Signaling Pathway
The 7-Acetylsinumaximol B (7-AB), a bioactive cembranoid, was originally discovered from aquaculture soft coral Sinularia sandensis. The current study investigated the anti-proliferative property of 7-AB towards the NCI-N87 human gastric cancer cell line. An MTT cell proliferative assay was applied...
Main Authors: | Tsung-Chang Tsai, Kuei-Hung Lai, Jui-Hsin Su, Yu-Jen Wu, Jyh-Horng Sheu |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-03-01
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Series: | Marine Drugs |
Subjects: | |
Online Access: | http://www.mdpi.com/1660-3397/16/4/104 |
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