Antidepressant effects of Kai-Xin-San in fluoxetine-resistant depression rats

Antidepressant effects of Kai-Xin-San in fluoxetine-resistant depression rats

This study aimed to investigate the antidepressant effect and the mechanism of action of Kai-Xin-San (KXS) in fluoxetine-resistant depressive (FRD) rats. Two hundred male Wistar rats weighing 200±10 g were exposed to chronic and unpredictable mild stresses (CUMS) for 4 weeks and given fluoxetine tre...

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Bibliographic Details
Main Authors: X.Z. Dong, D.X. Wang, Y.P. Lu, S. Yuan, P. Liu, Y. Hu
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2017-08-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Kai-Xin-San
Fluoxetine-resistant depression
Chronic unpredictable mild stress
Inflammatory factor
Anti-depression
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017001000601&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017001000601&lng=en&tlng=en

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