Membrane Interactome of a Recombinant Fragment of Human Surfactant Protein D Reveals GRP78 as a Novel Binding Partner in PC3, a Metastatic Prostate Cancer Cell Line

Membrane Interactome of a Recombinant Fragment of Human Surfactant Protein D Reveals GRP78 as a Novel Binding Partner in PC3, a Metastatic Prostate Cancer Cell Line

Surfactant protein-D (SP-D), a member of the collectin family has been shown to induce apoptosis in cancer cells. SP-D is composed of an N-terminal collagen-like domain and a calcium-dependent carbohydrate recognition domain (CRD). Recently, we reported that a recombinant fragment of human SP-D (rfh...

Full description

Bibliographic Details
Main Authors: Gargi Thakur, Gajanan Sathe, Indra Kundu, Barnali Biswas, Poonam Gautam, Saad Alkahtani, Susan Idicula-Thomas, Ravi Sirdeshmukh, Uday Kishore, Taruna Madan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Immunology
Subjects:
surfactant protein D
GRP78
interactome analysis
prostate cancer
apoptosis
signaling
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.600660/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.600660/full

Similar Items