A polymorphism in the regulatory region of <it>PRNP </it>is associated with increased risk of sporadic Creutzfeldt-Jakob disease

A polymorphism in the regulatory region of <it>PRNP </it>is associated with increased risk of sporadic Creutzfeldt-Jakob disease

<p>Abstract</p> <p>Background</p> <p>Creutzfeldt-Jakob disease (CJD) is a rare transmissible neurodegenerative disorder. An important determinant for CJD risk and phenotype is the M129V polymorphism of the human prion protein gene (<it>PRNP</it>), but there...

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Bibliographic Details
Main Authors: Will Robert G, Knight Richard SG, Croes Esther A, Bishop Matthew T, Sanchez-Juan Pascual, van Duijn Cornelia M, Manson Jean C
Format: Article
Language:English
Published: BMC 2011-05-01
Series:BMC Medical Genetics
Subjects:
Creutzfeldt-Jakob disease
prion protein gene
molecular subtype
regulatory region
early onset
Online Access:http://www.biomedcentral.com/1471-2350/12/73

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http://www.biomedcentral.com/1471-2350/12/73

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