LC/MS analysis of stratum corneum lipids: ceramide profiling and discovery[S]

LC/MS analysis of stratum corneum lipids: ceramide profiling and discovery[S]

Ceramides (CERs) in the upper layer of the skin, the stratum corneum (SC), play a key role in the skin barrier function. In human SC, the literature currently reports 11 CER subclasses that have been identified. In this paper, a novel quick and robust LC/MS method is presented that allows the separa...

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Bibliographic Details
Main Authors: Jeroen van Smeden, Louise Hoppel, Rob van der Heijden, Thomas Hankemeier, Rob J. Vreeken, Joke A. Bouwstra
Format: Article
Language:English
Published: Elsevier 2011-06-01
Series:Journal of Lipid Research
Subjects:
liquid chromatography
mass spectrometry
sphingolipids
human skin lipids
normal-phase liquid chromatography
atmospheric pressure chemical ionization mass spectrometry
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520313390

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http://www.sciencedirect.com/science/article/pii/S0022227520313390

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