A novel multistage antiplasmodial inhibitor targeting Plasmodium falciparum histone deacetylase 1

A novel multistage antiplasmodial inhibitor targeting Plasmodium falciparum histone deacetylase 1

Abstract Although artemisinin combination therapies have succeeded in reducing the global burden of malaria, multidrug resistance of the deadliest malaria parasite, Plasmodium falciparum, is emerging worldwide. Innovative antimalarial drugs that kill all life-cycle stages of malaria parasites are ur...

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Bibliographic Details
Main Authors: Zhenghui Huang, Ruoxi Li, Tongke Tang, Dazheng Ling, Manjiong Wang, Dandan Xu, Maoxin Sun, Lulu Zheng, Feng Zhu, Hui Min, Rachasak Boonhok, Yan Ding, Yuhao Wen, Yicong Chen, Xiaokang Li, Yuxi Chen, Taiping Liu, Jiping Han, Jun Miao, Qiang Fang, Yaming Cao, Yun Tang, Jie Cui, Wenyue Xu, Liwang Cui, Jin Zhu, Gary Wong, Jian Li, Lubin Jiang
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Cell Discovery
Online Access:https://doi.org/10.1038/s41421-020-00215-4

Internet

https://doi.org/10.1038/s41421-020-00215-4

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