Generation of mouse-zebrafish hematopoietic tissue chimeric embryos for hematopoiesis and host-pathogen interaction studies

Generation of mouse-zebrafish hematopoietic tissue chimeric embryos for hematopoiesis and host-pathogen interaction studies

Xenografts of the hematopoietic system are extremely useful as disease models and for translational research. Zebrafish xenografts have been widely used to monitor blood cancer cell dissemination and homing due to the optical clarity of embryos and larvae, which allow unrestricted in vivo visualizat...

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Bibliographic Details
Main Authors: Margarita Parada-Kusz, Cristina Penaranda, Elliott J. Hagedorn, Anne Clatworthy, Anil V. Nair, Jonathan E. Henninger, Christoph Ernst, Brian Li, Raquel Riquelme, Humberto Jijon, Eduardo J. Villablanca, Leonard I. Zon, Deborah Hung, Miguel L. Allende
Format: Article
Language:English
Published: The Company of Biologists 2018-11-01
Series:Disease Models & Mechanisms
Subjects:
Zebrafish
Xenotransplantation
Live imaging
Hematopoiesis
Cell migration
Host-pathogen interactions
Online Access:http://dmm.biologists.org/content/11/11/dmm034876

Internet

http://dmm.biologists.org/content/11/11/dmm034876

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