Albiflorin Promotes Osteoblast Differentiation and Healing of Rat Femoral Fractures Through Enhancing BMP-2/Smad and Wnt/β-Catenin Signaling

Albiflorin Promotes Osteoblast Differentiation and Healing of Rat Femoral Fractures Through Enhancing BMP-2/Smad and Wnt/β-Catenin Signaling

Fracture healing is related to osteogenic differentiation and mineralization. Recently, due to the unwanted side effects and clinical limitations of existing treatments, various natural product-based chemical studies have been actively conducted. Albiflorin is a major ingredient in Paeonia lactiflor...

Full description

Bibliographic Details
Main Authors: Jae-Hyun Kim, Minsun Kim, SooYeon Hong, Eun-Young Kim, Hyangsook Lee, Hyuk-Sang Jung, Youngjoo Sohn
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Pharmacology
Subjects:
Paeonia lactiflora
albiflorin
osteoblast
bone morphogenetic protein 2
runt-related transcription factor 2
Wnt
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.690113/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.690113/full

Similar Items