Free fatty acids, lipopolysaccharide and IL-1α induce adipocyte manganese superoxide dismutase which is increased in visceral adipose tissues of obese rodents.

Free fatty acids, lipopolysaccharide and IL-1α induce adipocyte manganese superoxide dismutase which is increased in visceral adipose tissues of obese rodents.

Excess fat storage in adipocytes is associated with increased generation of reactive oxygen species (ROS) and impaired activity of antioxidant mechanisms. Manganese superoxide dismutase (MnSOD) is a mitochondrial enzyme involved in detoxification of ROS, and objective of the current study is to anal...

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Bibliographic Details
Main Authors: Sabrina Krautbauer, Kristina Eisinger, Markus Neumeier, Yvonne Hader, Roland Buettner, Peter M Schmid, Charalampos Aslanidis, Christa Buechler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3901719?pdf=render

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http://europepmc.org/articles/PMC3901719?pdf=render

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