Revisiting the role of acetylcholinesterase in Alzheimer’s disease: cross-talk with P-tau and β-amyloid

Revisiting the role of acetylcholinesterase in Alzheimer’s disease: cross-talk with P-tau and β-amyloid

A common feature in the Alzheimer’s disease (AD) brain is the presence of acetylcholinesterase (AChE) which is commonly associated with β-amyloid plaques and neurofibrillary tangles. Although our understanding of the relationship between AChE and the pathological features of AD is incomplete, increa...

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Bibliographic Details
Main Authors: Maria-Salud eGarcía-Ayllón, David H eSmall, Jesus eAvila, Javier eSaez-Valero
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-09-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Acetylcholinesterase
β-Amyloid
Alzheimer’s disease
presenilin 1
P-tau
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2011.00022/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnmol.2011.00022/full

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