Design, Synthesis, and In Vivo and In Silico Evaluation of Coumarin Derivatives with Potential Antidepressant Effects

In this study, a series of coumarin derivatives were designed and synthesized, their structures were characterized using nuclear magnetic resonance (NMR) and high-resolution mass spectrometry (HRMS) testing methods. In the pharmacological experiment, two behavior-monitoring methods, the forced swim...

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Bibliographic Details
Main Authors: Xuekun Wang, Hao Zhou, Xinyu Wang, Kang Lei, Shiben Wang
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Molecules
Subjects:
FST
Online Access:https://www.mdpi.com/1420-3049/26/18/5556