Machupo virus glycoprotein determinants for human transferrin receptor 1 binding and cell entry.

Machupo virus glycoprotein determinants for human transferrin receptor 1 binding and cell entry.

Machupo virus (MACV) is a highly pathogenic New World arenavirus that causes hemorrhagic fever in humans. MACV, as well as other pathogenic New World arenaviruses, enter cells after their GP1 attachment glycoprotein binds to their cellular receptor, transferrin receptor 1 (TfR1). TfR1 residues essen...

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Bibliographic Details
Main Authors: Sheli R Radoshitzky, Lindsay E Longobardi, Jens H Kuhn, Cary Retterer, Lian Dong, Jeremiah C Clester, Krishna Kota, John Carra, Sina Bavari
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3131282?pdf=render

Internet

http://europepmc.org/articles/PMC3131282?pdf=render

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