Olmesartan Attenuates the Impairment of Endothelial Cells Induced by Oxidized Low Density Lipoprotein through Downregulating Expression of LOX-1

Olmesartan Attenuates the Impairment of Endothelial Cells Induced by Oxidized Low Density Lipoprotein through Downregulating Expression of LOX-1

Oxidized low density lipoprotein (ox-LDL) and its receptor, lectin-Like ox-LDL receptor-1 (LOX-1), play important roles in the development of endothelial injuries. Olmesartan can protect endothelial cells from the impairment caused by various pathological stimulations. In the present study we invest...

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Bibliographic Details
Main Authors: Ruolong Zheng, Wenlong Jiang, Xinjun Chen, Yuyu Yao, Weizhang Li, Huidong Qian, Genshan Ma, Hua Zhang
Format: Article
Language:English
Published: MDPI AG 2012-02-01
Series:International Journal of Molecular Sciences
Subjects:
olmesartan
lox-1 receptor
endothelial cells
oxidized low density lipoprotein
apoptosis
Online Access:http://www.mdpi.com/1422-0067/13/2/1512/

Internet

http://www.mdpi.com/1422-0067/13/2/1512/

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