IRBIT Directs Differentiation of Intestinal Stem Cell Progeny to Maintain Tissue Homeostasis

Summary: The maintenance of the intestinal epithelium is ensured by the controlled proliferation of intestinal stem cells (ISCs) and differentiation of their progeny into various cell types, including enterocytes (ECs) that both mediate nutrient absorption and provide a barrier against pathogens. Th...

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Bibliographic Details
Main Authors: Alexei Arnaoutov, Hangnoh Lee, Karen Plevock Haase, Vasilisa Aksenova, Michal Jarnik, Brian Oliver, Mihaela Serpe, Mary Dasso
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220301383