Structural determinants of nuclear export signal orientation in binding to exportin CRM1
The Chromosome Region of Maintenance 1 (CRM1) protein mediates nuclear export of hundreds of proteins through recognition of their nuclear export signals (NESs), which are highly variable in sequence and structure. The plasticity of the CRM1-NES interaction is not well understood, as there are many...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2015-09-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/10034 |