Identification of New Genes Involved in Germline Predisposition to Early-Onset Gastric Cancer

Identification of New Genes Involved in Germline Predisposition to Early-Onset Gastric Cancer

The genetic cause for several families with gastric cancer (GC) aggregation is unclear, with marked relevance in early-onset patients. We aimed to identify new candidate genes involved in GC germline predisposition. Whole-exome sequencing (WES) of germline samples was performed in 20 early-onset GC...

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Bibliographic Details
Main Authors: Cristina Herrera-Pariente, Roser Capó-García, Marcos Díaz-Gay, Sabela Carballal, Jenifer Muñoz, Joan Llach, Ariadna Sánchez, Laia Bonjoch, Coral Arnau-Collell, Yasmin Soares de Lima, Mariano Golubicki, Gerhard Jung, Juan José Lozano, Antoni Castells, Francesc Balaguer, Luis Bujanda, Sergi Castellví-Bel, Leticia Moreira
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
gastric cancer
whole-exome sequencing
germline predisposition
early-onset
somatic profiling
next-generation sequencing
Online Access:https://www.mdpi.com/1422-0067/22/3/1310

Internet

https://www.mdpi.com/1422-0067/22/3/1310

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