Cortical Reshaping and Functional Recovery Induced by Silk Fibroin Hydrogels-Encapsulated Stem Cells Implanted in Stroke Animals

Cortical Reshaping and Functional Recovery Induced by Silk Fibroin Hydrogels-Encapsulated Stem Cells Implanted in Stroke Animals

The restitution of damaged circuitry and functional remodeling of peri-injured areas constitute two main mechanisms for sustaining recovery of the brain after stroke. In this study, a silk fibroin-based biomaterial efficiently supports the survival of intracerebrally implanted mesenchymal stem cells...

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Bibliographic Details
Main Authors: Laura Fernández-García, José Pérez-Rigueiro, Ricardo Martinez-Murillo, Fivos Panetsos, Milagros Ramos, Gustavo V. Guinea, Daniel González-Nieto
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Cellular Neuroscience
Subjects:
brain remapping and plasticity
sensorimotor recovery
stroke
mesenchymal stem cells
silk fibroin hydrogels
somatosensory and motor cortex
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2018.00296/full

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https://www.frontiersin.org/article/10.3389/fncel.2018.00296/full

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