A novel method to establish glucocorticoid resistant acute lymphoblastic leukemia cell lines

Abstract Background Drug-resistant cell lines, established from drug-sensitive cell lines by drug exposure in vitro, are the most useful cancer models in studies on the mechanism of chemoresistance. However, the success rate of the traditional approaches to construct such cell lines is low because a...

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Bibliographic Details
Main Authors: Ling Gu, Ge Zhang, Yanle Zhang
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13046-019-1280-2