Treatment combining RU486 and Ad5IL-12 vector attenuates the growth of experimentally formed prostate tumors and induces changes in the sentinel lymph nodes of mice
<p>Abstract</p> <p>Background</p> <p>Tumor immune responses are first generated and metastases often begin in tumor sentinel lymph nodes (TSLN). Therefore, it is important to promote tumor immunity within this microenvironment. Mifepristone (RU486) treatment can interfe...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-10-01
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Series: | Journal of Translational Medicine |
Online Access: | http://www.translational-medicine.com/content/8/1/98 |