Treatment combining RU486 and Ad5IL-12 vector attenuates the growth of experimentally formed prostate tumors and induces changes in the sentinel lymph nodes of mice

Treatment combining RU486 and Ad5IL-12 vector attenuates the growth of experimentally formed prostate tumors and induces changes in the sentinel lymph nodes of mice

<p>Abstract</p> <p>Background</p> <p>Tumor immune responses are first generated and metastases often begin in tumor sentinel lymph nodes (TSLN). Therefore, it is important to promote tumor immunity within this microenvironment. Mifepristone (RU486) treatment can interfe...

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Bibliographic Details
Main Authors: Sercarz Eli E, Gauldie Jack, Graham Frank L, Halder Ramesh, Gee Jennifer, DeLaney Alexandra, Gabaglia Claudia, Braciak Todd A
Format: Article
Language:English
Published: BMC 2010-10-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/8/1/98

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http://www.translational-medicine.com/content/8/1/98

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