<i>Leishmania mexicana</i> Trypanothione Reductase Inhibitors: Computational and Biological Studies

<i>Leishmania mexicana</i> Trypanothione Reductase Inhibitors: Computational and Biological Studies

Leishmanicidal drugs have many side effects, and drug resistance to all of them has been documented. Therefore, the development of new drugs and the identification of novel therapeutic targets are urgently needed. <i>Leishmania mexicana</i> trypanothione reductase (LmTR), a NADPH-depende...

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Bibliographic Details
Main Authors: Félix Matadamas-Martínez, Alicia Hernández-Campos, Alfredo Téllez-Valencia, Alejandra Vázquez-Raygoza, Sandra Comparán-Alarcón, Lilián Yépez-Mulia, Rafael Castillo
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Molecules
Subjects:
trypanothione reductase
molecular docking
enzyme inhibitors
leishmanicidal activity
Online Access:https://www.mdpi.com/1420-3049/24/18/3216

Internet

https://www.mdpi.com/1420-3049/24/18/3216

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